Genome Evolution: Where Do New Introns Come From?
نویسندگان
چکیده
A new study reports creation of spliceosomal introns in multiple related fungal species by proliferation of cryptic elements. Resonances to a case in unrelated algae suggest such elements hold general answers to long-standing mysteries of intron evolution.
منابع مشابه
Intron Invasions Trace Algal Speciation and Reveal Nearly Identical Arctic and Antarctic Micromonas Populations
Spliceosomal introns are a hallmark of eukaryotic genes that are hypothesized to play important roles in genome evolution but have poorly understood origins. Although most introns lack sequence homology to each other, new families of spliceosomal introns that are repeated hundreds of times in individual genomes have recently been discovered in a few organisms. The prevalence and conservation of...
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In eukaryotes (and viruses), genes may be organized into coding and noncoding regions, called exons and (spliceosomal) introns, respectively (Box 1). Both types of sequences are transcribed into pre-mRNA, but whereas exons are used for protein synthesis, introns are spliced out during/immediately after transcription [1] (Figure 1). Although spliceosomal introns are widespread in the eukaryotic ...
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The role of spliceosomal intronic structures played in evolution has only begun to be elucidated. Comparative genomic analyses of fungal snoRNA sequences, which are often contained within introns and/or exons, revealed that about one-third of snoRNA-associated introns in three major snoRNA gene clusters manifested polymorphisms, likely resulting from intron loss and gain events during fungi evo...
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عنوان ژورنال:
- Current Biology
دوره 22 شماره
صفحات -
تاریخ انتشار 2012